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1-cyclohexyl-N-{[1-(4-methylphenyl)-1H-indol-3-yl]methyl}methanamine
- Development stage
- Preclinical
- Modality
- Small Molecules
01
Overview
This is a synthetic small molecule belonging to the class of phenylpyrroles and indole derivatives. It has been studied as an experimental agent, primarily for its activity as an inverse agonist or antagonist at the steroid hormone receptor ERRα (Estrogen-related receptor alpha, also known as ERR1). The compound has not been approved for any medical use and remains in preclinical or early-stage research. Its mechanism involves modulation of nuclear hormone receptors, which are implicated in metabolic regulation and potentially relevant to conditions such as gestational diabetes mellitus (GDM) and other metabolic disorders. No clinical trials or approved indications are reported for this molecule[2][5][6].
- Other names
- 1-Cyclohexyl-N-{[1-(4-methylphenyl)-1H-indol-3-yl]methyl}methanamine1-cyclohexyl-N-{[1-(4-méthylphényl)-1H-indol-3-yl]méthyl}méthanamine(cyclohexylmethyl)({[1-(4-methylphenyl)-1H-indol-3-yl]methyl})amine
02
Targets
ESRRA (Estrogen-related receptor alpha)
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